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Therini Bio

South San Francisco, California, United Statestherinibio.com ↗

Ownership: Private
Development stage: Phase 1

Overview

Therini Bio has completed a positive Phase 1a trial of its lead candidate THN391, a high-affinity humanized monoclonal antibody targeting fibrin-driven neuroinflammation. The therapy was well-tolerated with no serious adverse events or impact on coagulation, supporting once-monthly dosing. Preclinical data also support efficacy in models of Alzheimer’s disease and diabetic macular edema. The company plans to initiate further clinical studies in these indications.

Therapeutic areas: OphthalmologyNeurology
Modalities: Monoclonal antibodies (mAbs)Bispecific antibodies (in development)
Industry: Biotech

Drug pipeline

3 assets

THN391

2 more assets in the full pipeline.

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