THE-630
Phase 1- Indications
- Gastrointestinal stromal tumor
Company intelligence / Profile preview
Theseus Pharmaceuticals was a clinical-stage biopharmaceutical company focused on developing next-generation small molecule pan-varient tyrosine kinase inhibitors to overcome resistance mutations in key oncogenes. Its lead program, THE‑630, targeted all classes of activating and resistance mutations in the KIT receptor for GIST and was in Phase I/II trials. Additional programs included a fourth-generation EGFR inhibitor for NSCLC and a BCR–ABL inhibitor for CML and Ph+ ALL. The company was acquired by Concentra Biosciences in February 2024.
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