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Thetis Pharmaceuticals
Branford, Connecticut (CT), United Statesthetispharma.com ↗
- Ownership
- Private
- Development stage
- Phase 1
01
Overview
TP-317 is a first-in-class oral small molecule drug candidate based on Resolvin E1 that selectively engages the BLT1 receptor to promote tissue repair and restore immune homeostasis. It has demonstrated safety and tolerability in a Phase 1a single ascending dose study in healthy volunteers. Preclinical data show gut barrier protection, inflammation reduction, pain relief for IBD indications; also promising anti-tumor activity alone or combined with immunotherapy or chemotherapy in solid tumors. New data presented at ECCO 2025 further validate its mechanism of action[6][8][9].
- Therapeutic areas
- GastroenterologyOncology
- Modalities
- Small molecule drugs derived from bioactive lipids called Resolvins, specifically Resolvin E1-based compounds
- Industry
- Biotech
02
Drug pipeline
6 assets5 more assets in the full pipeline.
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