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ABCB5-positive mesenchymal stem cells, developed and manufactured by TICEBA (now part of RHEACELL), have demonstrated anti-inflammatory and tissue-regenerative effects. Their cell therapy (AMESANAR®) is approved in Germany for chronic venous ulcers, and late-stage clinical trials (including pivotal Phase 3) are ongoing for epidermolysis bullosa (EBESANAR®); additional clinical studies are underway for other inflammation-driven and rare diseases.
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