Company intelligence / Profile preview
TopiVert Pharma Limited
London, England, United Kingdomtopivert.com ↗
- Ownership
- Private
- Development stage
- Other
01
Overview
TopiVert developed locally acting small molecule kinase inhibitors for chronic inflammatory diseases of the GI tract and eye. Lead program TOP1288 showed strong safety and pharmacodynamic data in a Phase I study for ulcerative colitis. Ophthalmology candidate TOP1630 demonstrated proof-of-concept efficacy in dry eye syndrome with positive results from a US-based Phase I/IIa trial. A multicenter randomized placebo-controlled phase IIb/III trial was underway for DED as of the last reports. The company’s NSKI technology aimed to provide potent anti-inflammatory effects with minimal systemic exposure.
- Therapeutic areas
- GastroenterologyOphthalmology
- Modalities
- Small molecules (specifically Narrow Spectrum Kinase Inhibitors, NSKIs)
- Industry
- Biotech
02
Drug pipeline
3 assets2 more assets in the full pipeline.
03
Partnerships
No major pharma partnerships disclosed; investors include Johnson & Johnson Innovation – JJDC, Inc., SV Health Investors, Touchstone Innovations, NeoMed.
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