Company intelligence / Profile preview
TopiVert Pharma Limited
- Ownership
- Private
- Development stage
- Phase 2
Overview
TopiVert developed locally acting small molecule kinase inhibitors for chronic inflammatory diseases of the GI tract and eye. Lead program TOP1288 showed strong safety and pharmacodynamic data in a Phase I study for ulcerative colitis. Ophthalmology candidate TOP1630 demonstrated proof-of-concept efficacy in dry eye syndrome with positive results from a US-based Phase I/IIa trial. A multicenter randomized placebo-controlled phase IIb/III trial was underway for DED as of the last reports. The company’s NSKI technology aimed to provide potent anti-inflammatory effects with minimal systemic exposure.
- Therapeutic areas
- GastroenterologyOphthalmology
- Modalities
- Small molecules (specifically Narrow Spectrum Kinase Inhibitors, NSKIs)
- Industry
- Biotech
Drug pipeline
3 assets2 more assets in the full pipeline.
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