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Topokine Therapeutics

Ownership: Private
Development stage: Phase 3

Overview

Topokine’s lead asset, XAF5 Ointment, was in late-stage clinical development for the reduction of undereye bags. In a Phase 2 randomized controlled trial, XAF5 met its primary endpoint with statistically significant and clinically meaningful reductions in undereye bags. A pivotal Phase 2b/3 study was initiated in January 2016. The second program, TAT4 Gel for nasolabial folds, entered Phase 2 trials. The company’s assets were protected by over 75 issued and pending patents worldwide.

Therapeutic areas: Dermatology
Modalities: Topical small molecules (adipomodulatory medicines)
Industry: Biotech

Drug pipeline

2 assets

XAF5

Phase 3

Indications: Steatoblepharon, Localized obesity

1 more asset in the full pipeline.

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Partnerships

No major external partnerships disclosed prior to acquisition.

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