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Estrella Immunopharma is a preclinical biotech company developing CD19- and CD22-targeted T cell therapies for blood cancers and solid tumors, aiming to reduce the risk of Cytokine Release Syndrome compared to traditional CAR-T therapies. The company is a result of a business combination between TradeUP Acquisition Corp. (a special purpose acquisition company, or SPAC) and Estrella Biopharma, Inc., and began trading on NASDAQ as ESLA and ESLAW in October 2023. Its lead programs leverage the ARTEMIS platform, licensed from Eureka Therapeutics, and the company is collaborating with Imugene on a 'mark and kill' strategy for solid tumors. The company does not yet have clinical data; all programs are in preclinical development.
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