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Transition Therapeutics Inc.

Toronto, Ontario, Canadatransitionbio.com ↗
Ownership
Private
Development stage
Preclinical
01

Overview

Transition Therapeutics was a Toronto-based biopharmaceutical company focused on developing novel small molecule therapies targeting central nervous system disorders such as Alzheimer’s disease and metabolic diseases like type 2 diabetes. Its lead program ELND005 reached late-stage clinical trials for agitation/aggression in Alzheimer’s patients. The company also developed TT401 with Eli Lilly for diabetes/obesity and TT701 targeting androgen deficiency. In mid‑2016, the company was acquired by OPKO Health.

Therapeutic areas
EndocrinologyRare DiseasesNeurologyMen's Health
Modalities
Small moleculesSelective androgen receptor modulators (SARMs)Other novel therapeutics for CNS and metabolic diseases
Industry
Biotech
02

Partnerships

Eli Lilly & Co. — collaboration/licensing agreement on TT401/metabolic compounds development/commercializationElan Pharmaceuticals — partnership on ELND005 development for Alzheimer’s disease

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