Trestle Optics

Trestle Optics is a life science instrumentation company specializing in the development of advanced light-sheet microscopy systems for high-resolution 3D imaging. The company's flagship product, the Trestle microscope, features a multi-immersion design that allows for the rapid volumetric imaging of large, cleared biological specimens such as intact organs and thick tissue sections. By providing high-throughput and high-resolution imaging capabilities, Trestle Optics supports researchers in fields like neuroscience, developmental biology, and pathology. The technology is engineered to overcome the limitations of traditional confocal microscopy, offering significantly faster acquisition speeds and reduced phototoxicity for complex biological samples. Headquartered in Cambridge, Massachusetts, the company leverages expertise in optical engineering and biological imaging to provide tools that bridge the gap between traditional histology and modern volumetric analysis.