Company intelligence / Profile preview

Trethera

Santa Monica, California, USAtrethera.com ↗
Ownership
Private
Employees
~7
Development stage
Phase 1
01

Overview

TRE‑515, an orally delivered first-in-class inhibitor of deoxycytidine kinase, has received FDA Orphan Drug designation for two diseases. It has demonstrated tolerability and potential efficacy in early clinical development targeting both cancer and autoimmune disease by exploiting metabolic vulnerabilities unique to diseased cells. The company positions TRE‑515 as potentially safer with fewer side effects compared to traditional therapies.

Therapeutic areas
OncologyImmunologyRare Diseases
Modalities
Small molecules (notably oral small molecule inhibitors)
Industry
Biotech
02

Drug pipeline

1 asset

TRE-515

1
03

Partnerships

Collaborations with key academic groups including UCLA; pharmaceutical partnerships mentioned but not named specifically

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