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True North
South San Francisco, California, United Statesitstruenorth.com ↗
- Ownership
- Private
- Employees
- ~30
- Development stage
- Commercial
01
Overview
True North Therapeutics was a clinical-stage biotechnology company developing first-in-class monoclonal antibody therapies that selectively inhibit C1s, a key enzyme in the classical complement pathway. Its lead candidate, TNT009, advanced through early-phase clinical trials targeting rare hematological and immune-mediated disorders such as cold agglutinin disease. The company's approach aimed to address high unmet medical needs by modulating immune system overactivity without broadly suppressing immunity. The company was acquired before reaching commercial stage.
- Therapeutic areas
- DermatologyImmunologyHematology
- Modalities
- Monoclonal antibodyBiologic
- Industry
- Biotech
02
Partnerships
No major pharma partnerships disclosed prior to acquisition; investors included Bioverativ which later acquired it.
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