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TruLeaf Medical has completed R&D and long-term animal testing for its RoseDoc transcatheter mitral valve replacement (TMVR) platform, with approval received for the first-in-human clinical trial. The system allows minimally invasive replacement of the mitral valve for patients with severe mitral regurgitation, aiming to address a major unmet need for those inoperable by standard surgery. Preclinical studies demonstrated successful elimination of valve leak and improved cardiac function.
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