Tuning Fork Bio

Tuning Fork Bio is a biotechnology company established in 2023 as a spin-off from Yamaha Motor Company's healthcare initiatives. Headquartered in Delaware with R&D operations in Cambridge, Massachusetts, and Tokyo, Japan, the company specializes in antibody profiling and biomarker discovery. By combining high-density protein microarray technology developed in collaboration with Fukushima Medical University with proprietary AI and bioinformatics (Tuning-Base™), Tuning Fork Bio analyzes circulating antibodies in blood, serum, and saliva. This platform enables the identification of novel drug targets, therapeutic antibodies, and early diagnostic biomarkers for autoimmune diseases, cancers, and other conditions. The company provides contract profiling services to pharmaceutical partners and was recognized with the AbbVie Japan Innovation Award in 2026.