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Twinstrand Therapeutics

Winnipeg, Manitoba, Canadatwinstrandbio.com ↗

Ownership: Private
Development stage: Commercial

Overview

Twinstrand's lead drug, TST10088, was in Phase I clinical trials at the time of acquisition. The company's approach used modified versions of the plant toxin ricin as targeted prodrugs that are activated only within diseased cells, sparing healthy tissue. They also began developing antibody-based anti-toxin therapeutics for biodefense. No further clinical results are available post-acquisition.

Therapeutic areas: OncologyInfectious Diseases
Modalities: Modified protein toxins (ricin-based prodrugs)Antibody-based therapeutics
Industry: Biotech

Partnerships

Cangene Corporation had previously partnered with Twinstrand on anti-toxin technology before acquiring the company outright.

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