Twistle

Twistle is a healthcare technology company focused on digital patient engagement and care-plan automation rather than therapeutics development. Its platform enables healthcare providers to automate personalized, HIPAA-compliant communication with patients across channels such as SMS, mobile, portals, and IVR to support education, reminders, follow-up, and surveillance. The company’s software is used to improve adherence, reduce readmissions and no-shows, and streamline care-team workflows by integrating outreach into clinical and operational systems. Twistle was founded in 2011 and was acquired by Health Catalyst in 2021, after which it has continued to operate commercially as "Twistle by Health Catalyst." It is best characterized as a commercial healthcare IT and patient engagement platform business, including offerings relevant to providers and life sciences organizations.