Twitch

Twitch Therapeutics is a pre-clinical stage biotechnology company developing targeted gene therapies for chronic pain and neuromuscular diseases. The company leverages a proprietary platform to engineer lipid nanoparticles (LNPs) that can selectively deliver genetic payloads to the peripheral nervous system. By targeting specific ion channels and signaling pathways involved in pain transmission, Twitch aims to provide long-lasting, non-opioid relief with minimal systemic side effects. Their approach represents a significant shift from traditional small molecule treatments toward precision genetic medicine for neurological conditions. The company was founded by experts in LNP delivery and is backed by prominent venture capital firms.