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The BEHOLD Phase 2 study demonstrated that a single injection of UBX1325 resulted in statistically significant and clinically meaningful improvement in vision through 48 weeks in patients with diabetic macular edema[4]. The ASPIRE Phase 2b study is currently evaluating UBX1325 head-to-head against aflibercept in patients with diabetic macular edema[2]. However, a previous osteoarthritis trial with UBX0101 failed in 2020, causing a 60% drop in share price[4].
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