Company intelligence / Profile preview

Unleash Immuno Oncolytics

St. Louis, Missouri, United Statesoncolys.com ↗
Ownership
Private
Development stage
Preclinical
01

Overview

Unleash Immuno Oncolytics develops genetically engineered oncolytic adenoviruses designed to target both malignant cancer cells and the supportive stromal environment that enables metastasis. Their lead candidate, UIO‑512, aims at refractory solid tumors by infecting both tumor and stroma cells. Another program, UIO‑702, incorporates a camelid antibody into the viral fiber to evade human immune responses for systemic delivery against metastatic cancers. The company has attracted investment from strategic partners such as Oncolys BioPharma but has not yet reported clinical trial results or late-stage data.

Therapeutic areas
Oncology
Modalities
Genetically engineered oncolytic adenovirusesCancer immunotherapy virusesViruses with incorporated camelid antibodies (for immune evasion)
Industry
Biotech
02

Drug pipeline

1 asset

UIO-525

Unknown
03

Partnerships

Oncolys BioPharma Inc.—strategic investor and collaborator; holds board seat at Unleash Immuno Oncolytics.Precision Virologics—Unleash held shares in this Washington University biotech venture related to gene-modification technology.

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