Vascular Closure Systems

Vascular Closure Systems, Inc. was a medical device company based in San Francisco, California, focused on the development and commercialization of bioabsorbable vascular access closure technology. The company's lead product, the FastSeal Bioabsorbable Vascular Access Closure System, was designed to achieve rapid hemostasis following catheter-based procedures by deploying a bioabsorbable sealing element. FastSeal was compatible with standard 6 Fr and 7 Fr introducer sheaths and featured a safety tether for removal if malpositioned during deployment. The company successfully completed Phase I and Phase II first-in-human clinical trials in Italy, demonstrating normal vessel healing and complete absorption of the device. Despite achieving ISO 13485 compliance and holding a significant patent portfolio, the company is currently inactive.