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Vast Therapeutics is developing nitric oxide-based small molecule therapies delivered via inhalation to treat chronic respiratory diseases. Their lead programs are in preclinical and early clinical stages targeting cystic fibrosis, non-CF bronchiectasis, NTM disease, and COPD. The approach aims to break the cycle of infection and inflammation with novel antimicrobial agents that are not susceptible to traditional resistance mechanisms. No published clinical results yet.
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