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In Phase 1 clinical trials, VLS-101 demonstrated a manageable safety profile and early signs of anti-tumor activity. Results showed objective clinical responses in 47% (7/15) of patients with mantle cell lymphoma and 80% (4/5) of patients with diffuse large B-cell lymphoma. Some patients achieved complete responses. These patients had been heavily pretreated with other anticancer medications before receiving VLS-101[2][8].
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