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Vigil Neuroscience

Watertown, Massachusetts, United Statesvigilneuro.com ↗
Ownership
Private
Employees
~200
Development stage
Phase 2
01

Overview

Vigil Neuroscience is advancing two TREM2 agonist programs: iluzanebart (monoclonal antibody) in Phase 2 for ALSP with final analysis planned for Q2 2025, and VG-3927 (small molecule) in Phase 1 for Alzheimer's disease with data expected in Q1 2025. Interim Phase 1 data for VG-3927 showed robust decrease of sTREM2 in CSF demonstrating clinical proof-of-target engagement[6].

Therapeutic areas
Neurology
Modalities
Monoclonal antibodiesSmall molecules
Industry
Biotech
02

Drug pipeline

1 asset

iluzanebart

Discontinued
03

Partnerships

Sanofi (strategic investment of $40 million in 2024)[3]

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