Virella

Virella is a Slovenian biotechnology company specializing in the development of novel small molecule therapeutics that activate Sirtuin 6 (SIRT6), a master regulator of aging and genomic stability. The company's proprietary platform is based on chemical scaffolds derived from griseofulvin, which have demonstrated potent SIRT6 activation and longevity-extending effects in C. elegans models. Virella is currently in the lead optimization stage, targeting a range of age-related conditions including metabolic diseases, oncology, and osteoarthritis. By restoring SIRT6 function, the company aims to address fundamental mechanisms of biological aging and DNA repair to treat significant unmet medical needs.