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Vitae advanced several novel small molecules to Phase 2, including VTP-38543 for atopic dermatitis (topical LXRβ agonist), VTP-43742 for autoimmune/dermatological indications, VTP-201227 for psoriasis (enzyme inhibitor), and VTP-195183 for oncology (nuclear receptor agonist to mobilize progenitor cells); all showed early favorable safety/tolerability in phase 1 and initial phase 2 proof-of-concept studies
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