Company intelligence / Profile preview

Vivet Therapeutics

Ownership
Private
Employees
~40
Development stage
Phase 2
01

Overview

Vivet Therapeutics' lead program, VTX‑801 for Wilson disease, has shown encouraging interim results in its Phase 1/2 GATEWAY trial with increased ceruloplasmin ferroxidase activity and improved liver histology. No serious adverse events have been reported so far. The company also received significant funding to advance its second program targeting CTX. Additional pipeline assets target rare inherited metabolic disorders affecting the liver.

Therapeutic areas
GastroenterologyMetabolic DisordersRare Diseases
Modalities
Gene therapy (AAV vector-based)Recombinant adeno-associated viruses (rAAVs)
Industry
Biotech
02

Drug pipeline

8 assets

VTX-806

Preclinical

7 more assets in the full pipeline.

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03

Partnerships

Pfizer Inc. — manufacturing agreement, equity investment (~15%), exclusive option to acquire all shares; co-development on VTX–801/Wilson Disease program.Fundación para la Investigación Médica Aplicada/CIMA University of Navarra — technology licensing partner.Mirum Pharmaceuticals — acquired rights to develop/commercialize VTX–802 & VTX–803 in US as of 2021.BPiFrance/French government — non-dilutive grant support.Patient advocacy groups including CTX Alliance and Spanish CTX patient association.

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