Company intelligence / Profile preview

Vor Bio

Cambridge, Massachusetts, United Statesvorbio.com ↗
Ownership
Public · VOR
Employees
~159
Development stage
Phase 1
01

Overview

Vor Bio’s lead program involves gene-editing donor hematopoietic stem cells to remove CD33 expression (“trem-cel”), allowing patients to receive anti-CD33 therapies such as Mylotarg without damaging healthy blood cells. Early clinical results are promising for enabling targeted therapy post-transplant while protecting normal hematopoiesis. Multiple clinical trials are ongoing for AML and MDS patients.

Therapeutic areas
OncologyHematology
Modalities
Hematopoietic stem cell (HSC) transplants (gene-edited)Chimeric Antigen Receptor T cells (CAR-T)Antibody Drug Conjugates (ADCs)
Industry
Biotech
02

Drug pipeline

15 assets

dual CD33-CLL1 CAR-T cells

1

14 more assets in the full pipeline.

03

Partnerships

No major pharma partnerships disclosed; collaborations with academic founders.Scientific & Clinical Advisors include leading experts in oncology and cell/gene therapy fields.
04

Financials

Market cap
$1B
Total revenue
$0
Enterprise value
$532.4M

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