Company intelligence / Profile preview
VST Bio
San Diego, California, United Statesvst-bio.com ↗
- Ownership
- Private
- Development stage
- Preclinical
01
Overview
VST Bio has developed fully human/humanized monoclonal antibodies that selectively regulate pathological vascular permeability by targeting novel mechanisms downstream of VEGF signaling. In preclinical models, these antibodies have demonstrated significant reduction in cerebral damage after stroke, improved cardiac function post-myocardial infarction, reduced mortality in septic shock models, and decreased cytokine storm. The lead program has shown up to a ~50–80% reduction in brain damage following acute ischemic stroke in animal studies. The company expects clinical proof-of-concept data by late Q4 2026.
- Therapeutic areas
- CardiovascularOphthalmologyOncologyNeurologyInfectious Diseases
- Modalities
- Humanized antibodiesFully human antibodies
- Industry
- Biotech
02
Drug pipeline
2 assets1 more asset in the full pipeline.
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Partnerships
Exclusive license from Yale University covering all therapeutic rights related to their molecular pathway technology regulating vascular permeability.
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