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VX3 is an early-stage biotechnology company focused on the development of novel small molecule inhibitors for the treatment of cancer. The company's primary research efforts center on targeting the ubiquitin-proteasome system, specifically focusing on the inhibition of Ubiquitin-specific protease 1 (USP1). By targeting USP1, VX3 aims to disrupt DNA damage repair pathways in cancer cells, particularly those with specific genetic vulnerabilities such as BRCA mutations. The company is currently advancing its lead programs through pre-clinical development to address unmet needs in solid tumors, including breast and ovarian cancers.
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