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Medera is a clinical-stage biopharmaceutical company focused on cardiovascular diseases, operating through two specialized units: Novoheart and Sardocor. Novoheart utilizes its proprietary "mini-Heart" (Heart-in-a-Jar) platform for drug discovery and disease modeling, while Sardocor focuses on the clinical development of next-generation gene therapies. The company’s lead candidate, SRD-001, is an adeno-associated virus (AAV) gene therapy targeting the SERCA2a protein to restore cardiac calcium handling in patients with heart failure and Duchenne muscular dystrophy-associated cardiomyopathy. Medera leverages human-based bioengineered heart models to accelerate drug testing and reduce reliance on animal studies, in alignment with the FDA Modernization Act 2.0. The company went public via a merger with a special purpose acquisition company (SPAC) in late 2024.
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