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Xilio Development

Waltham, Massachusetts, United States
Ownership
Public · XLO
Employees
~70
Development stage
Other
01

Overview

Xilio Therapeutics has reported early-phase clinical results for its lead candidates, including vilastobart (masked anti-CTLA-4 + PD-L1) in combination with atezolizumab and efarindodekin alfa (masked IL-12), demonstrating tumor-selective activation with the aim to improve efficacy and minimize systemic toxicity in various advanced solid tumors and colorectal cancer. Several other programs are in preclinical and IND-enabling stages.

Therapeutic areas
Oncology
Modalities
AntibodyBispecific monoclonal antibodyCytokineProtein
Industry
Biotech
02

Partnerships

AbbVie (collaboration and option agreement for tumor-activated immunotherapies as of February 2025)

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