Company intelligence / Profile preview

XL-protein

Freising/Weihenstephan, Bavaria, Germanyxl-protein.com ↗
Ownership
Private
Employees
~8
Development stage
Commercial
01

Overview

XL-protein develops biopharmaceuticals using its proprietary PASylation® technology to extend plasma half-life of therapeutic proteins. This enables less frequent dosing and improved tolerability. The company has demonstrated efficient production of hyperactive PASylated DNase I with extended half-life and has an immunosuppressive PASylated antibody fragment supported by the Bavarian Research Foundation for cardiac xenotransplantation. Most results are preclinical, with some programs advancing toward early clinical phases through spin-outs or partnerships.

Therapeutic areas
OtherCardiovascular
Modalities
Recombinant proteinProtein (PASylated proteins)Polymer-drug conjugate therapy (PASylation as a polymer alternative to PEGylation)Biologic
Industry
Biotech
02

Drug pipeline

22 assets

hyperactive PASylated DNase I

Preclinical

21 more assets in the full pipeline.

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03

Partnerships

Rentschler Biopharma (production collaboration)multiple undisclosed international pharma/biotech partners at various levels

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