Company intelligence / Profile preview

XORTX Therapeutics

Calgary, Alberta, Canadaxortx.com ↗
Ownership
Public · XRTX
Employees
~3
Development stage
NDA
01

Overview

XORTX’s most advanced program for gout (XORLO™, reformulated oxypurinol) has secured FDA agreement to use the 505(b)(2) pathway and expects an NDA submission by H1 2026. The ADPKD program (XRx‑008) and COVID-related acute kidney injury program are in Phase 2 development. A preclinical candidate targets type 2 diabetic nephropathy. The company’s approach leverages established safety data for oxypurinol to accelerate regulatory timelines.

Therapeutic areas
EndocrinologyNephrologyRheumatology
Modalities
small molecules (notably xanthine oxidase inhibitors and uric acid lowering agents)
Industry
Biotech
02

Drug pipeline

4 assets

oxypurinol

3

3 more assets in the full pipeline.

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03

Partnerships

University of Florida Research Foundation license agreement for use of a uric acid-lowering agent to treat insulin resistanceCollaboration with PKD Foundation on ADPKD research
04

Financials

Market cap
$587.6K
Total revenue
$0
Enterprise value
$-405.2K

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