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Xsphera Biosciences

Cambridge/Boston*, Massachusetts, United Statesxspherabio.com ↗
Ownership
Private
Development stage
Preclinical
01

Overview

Xsphera Biosciences has developed an ex vivo human tumor tissue-based testing platform that enables direct assessment of therapeutic efficacy across diverse cancer indications and drug modalities. Their technology preserves the patient’s unique tumor microenvironment within microfluidic devices, allowing multi-modal analysis of immune-mediated responses. The system is integrated with an AI-driven cloud analytics suite for deep mechanistic insights into response and resistance. The company collaborates with leading pharma/biotech clients globally, supporting translational research from preclinical through early clinical development.

Therapeutic areas
Oncology
Modalities
BiologicSmall moleculeMonoclonal antibodyBispecific monoclonal antibodyAntibody-drug conjugateOncolytic virus therapy
Industry
Biotech
02

Partnerships

Dana-Farber Cancer Institute (exclusive technology license)NEX-I (collaboration on immune-oncology therapeutics evaluation; NXI–101 program)

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