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Yingkai Saiwei Biotechnology is developing a mutant KRAS G12V-specific TCR transduced T cell therapy for advanced and metastatic solid tumors. Its lead program, YK0901, is in Phase 1 clinical trials with Peking University as the sponsor. The trial targets patients with advanced malignant neoplasms harboring the KRAS G12V mutation; as of July 2023, recruitment had not yet started and no clinical results have been published.
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