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Zanos is a biotechnology company pioneering the development of therapeutics that target Z-nucleic acids (Z-DNA and Z-RNA) and their associated binding proteins. The company focuses on the ZBP1 and ADAR1 pathways, which play critical roles in innate immunity, cell death (necroptosis), and inflammation. By modulating these pathways, Zanos aims to treat a variety of cancers and inflammatory disorders where Z-nucleic acid signaling is dysregulated. The company's approach leverages deep expertise in the structural biology of alternative DNA/RNA conformations to unlock new classes of precision medicines.
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