Company intelligence / Profile preview

Zelos Therapeutics

Conshohocken, Pennsylvania, USAir.neximmune.com ↗
Ownership
Private
Employees
~4
Development stage
Phase 3
01

Overview

ZT‑031 (Ostabolin-C), a proprietary cyclic parathyroid hormone analog, demonstrated strong bone formation activity with rapid onset and clinically significant increases in bone mineral density at low toxicity doses. The subcutaneous formulation completed a successful 12-month Phase 2 trial in postmenopausal women with low bone mass. Intranasal and inhaled versions were also developed through partnerships.[6] The company planned to enter Phase 3 trials before restructuring as Azelon Pharmaceuticals.[7] As Azelon, the nasal spray ZT‑034 entered early clinical studies.

Therapeutic areas
OtherEndocrinologyNephrology
Modalities
Peptides (parathyroid hormone analogs)Small proteins[6][8][10]
Industry
Biotech
02

Drug pipeline

1 asset

ostabolin-c

Discontinued
03

Partnerships

Aegis Therapeutics LLC – collaboration on intranasal delivery using Intravail® technology[5]Nektar Therapeutics – collaboration on inhaled powder formulation of Ostabolin-C using Nektar’s inhaler device technology[8][10]

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