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Juvensis Therapeutics is a clinical-stage biotechnology company based in China, focused on developing innovative gene therapies for heart failure and age-related degenerative diseases. Founded in 2021, the company leverages a proprietary telomere precision modulation technology platform to address the telomere-mitochondria axis of aging. Its lead candidate, JV101, is an AAV9-delivered gene therapy that expresses a modified, catalytically inactive human telomerase reverse transcriptase (hTERT) to recap telomeres, suppress DNA damage responses, and restore mitochondrial biogenesis in cardiomyocytes. Juvensis has received recognition from global pharmaceutical leaders like Novo Nordisk and Boehringer Ingelheim and is advancing a pipeline targeting cardiovascular, neurological, and renal indications.
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