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ZKR Orthopedics

San Francisco, California, United Stateszkrorthopedics.com ↗

Ownership: Private
Development stage: Phase 1

Overview

The LIFT implant has demonstrated significant improvement in pain and function for patients with moderate to severe patellofemoral cartilage degeneration. In a two-year European pilot study with 18 patients, there was high patient satisfaction, no progression to knee replacement, and no severe adverse events. The ongoing pivotal PELICAN trial will compare outcomes against tibial tubercle osteotomy at multiple US and European sites. The LIFT technology received FDA Breakthrough Device Designation in late 2023.

Therapeutic areas: Rheumatology
Modalities: Device (specifically implantable orthopedic devices)Non-pharmacological therapy (surgical intervention)
Industry: Implantable Medical Devices

Drug pipeline

1 asset

Patella LIFT Implant

Phase 1

Indications: Patellofemoral arthritis, Chondromalacia patella, Cartilage degeneration

Partnerships

None publicly disclosed as of June 2025.

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