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β1 integrin siRNA
- Development stage
- Unknown
- Modality
- Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Conjugated siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
- Administration
- Intraperitoneal, Intravenous
01
Overview
β1 integrin siRNA is a small interfering RNA (siRNA) designed to target and silence the expression of the β1 integrin (ITGB1) gene. β1 integrin is a cell surface receptor that plays a critical role in cell-extracellular matrix (ECM) adhesion, cell signaling, migration, and tumor progression. In research settings, β1 integrin siRNA is widely used to investigate the functional roles of β1 integrin in cancer cell invasion, metastasis, drug resistance, and tissue regeneration. Silencing of β1 integrin has been shown to alter cell migration strategies, sensitize cancer cells to therapies, and affect cellular differentiation.
- Other names
- beta1 integrin siRNAbeta-1 integrin siRNAbeta 1 integrin siRNAintegrin beta-1 siRNAintegrin beta1 siRNAITGB1 siRNAITGB-1 siRNAITGB 1 siRNA
02
Targets
ITGB1 (Integrin beta-1)
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