Drug intelligence / Profile preview

Йод-Актив

Development stage
Unknown
Lead developer
Diod
Modality
Recombinant Proteins and Enzymes, Small Molecules
Administration
Oral
01

Overview

Йод-Актив (Iod-Activ) is a dietary supplement developed by the Russian company Diod as a source of organic iodine to address iodine deficiency and support thyroid health. The active component is iodocasein, which consists of iodine covalently bound to the milk protein casein. This formulation is marketed as "smart iodine" because its absorption is regulated by the body's physiological needs: in the presence of iodine deficiency, liver enzymes (produced in response to the deficiency) cleave the iodine from the protein for absorption, whereas excess iodine remains bound to the protein and is excreted. It was developed in collaboration with the Medical Radiological Scientific Center of the Russian Academy of Medical Sciences, based on research into thyroid disease prevention following the Chernobyl accident.

Brand names
Йод-АктивIod-ActivЙод-Актив 100
Other names
iodocaseinЙодказеин
02

Targets

TPO (Thyroid peroxidase)

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