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二十五味儿茶丸
- Development stage
- Unknown
- Lead developer
- Xizang Ganlu Tibetan Medicine
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
二十五味儿茶丸 (Twenty-Five Flavor Catechu Pills) is a traditional Tibetan medicine developed and manufactured by Xizang Ganlu Tibetan Medicine. It is an approved pharmaceutical product in China (National Drug License Number Z54020031) primarily indicated for the treatment of rheumatoid arthritis (RA), pain, and inflammation. The formulation is a complex mixture of 25 herbal and animal-derived ingredients, including *Acacia catechu*, *Aconitum pendulum*, and musk. Pharmacological studies suggest that the medicine exerts its therapeutic effects by modulating the immune response, specifically by downregulating pro-inflammatory cytokines such as tumor necrosis factor-alpha (TNF-α) and interleukin-6 (IL-6), while upregulating anti-inflammatory cytokines like interleukin-4 (IL-4) and interleukin-10 (IL-10). Additionally, research in animal models has indicated that the treatment may help restore gut microbiome balance associated with arthritic conditions.
- Brand names
- 二十五味儿茶丸
- Other names
- Twenty-Five Flavor Catechu PillsTwenty-Five Wei'er Tea PillsErcha Pills25-Flavor Catechu Pills
02
Targets
IL-6 (Interleukin 6)TNFA (Tumor necrosis factor alpha (soluble))IL-4 (Interleukin 4)IL10 (Interleukin-10)
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