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Drug intelligence / Profile preview
愈美甲麻敏糖浆
- Development stage
- Unknown
- Lead developer
- Shenyang Dongxing Pharmaceutical Technology
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
愈美甲麻敏糖浆 (Yu Mei Jia Ma Min Tang Jiang) is a multi-ingredient combination cough syrup developed and manufactured by Shenyang Dongxing Pharmaceutical Technology. The formulation contains four active ingredients: dextromethorphan hydrobromide, a centrally acting antitussive; guaifenesin, an expectorant; methylephedrine hydrochloride, a bronchodilator; and chlorpheniramine maleate, a first-generation antihistamine. This oral syrup is indicated for the symptomatic relief of coughs and respiratory symptoms associated with the common cold, bronchitis, and asthma. Dextromethorphan suppresses the cough reflex via sigma-1 receptor agonism and NMDA receptor antagonism, while guaifenesin facilitates the removal of mucus by reducing its viscosity. Methylephedrine acts as an adrenergic receptor agonist to relieve bronchospasm and airway congestion, and chlorpheniramine blocks H1 receptors to alleviate allergic symptoms such as sneezing and rhinorrhea. The product is approved and marketed in China as an over-the-counter (OTC) medication.
- Brand names
- 愈美甲麻敏糖浆
- Other names
- Compound Cough SyrupYu Mei Jia Ma Min Tang Jiang
02
Targets
ADRA1 (Alpha-1 adrenergic receptor family)ADRB1 (β1)HRH1 (Histamine H1 Receptor)NMDAR (Glutamate receptor ionotropic, NMDA)SIGMAR1 (Sigma non-opioid intracellular receptor 1)
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