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虎杖痛风颗粒
- Development stage
- Unknown
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
虎杖痛风颗粒 (HZKL) is a traditional Chinese medicine (TCM) formulation primarily used for the treatment of gout and hyperuricemia. The main ingredient is Polygonum cuspidatum (Japanese knotweed), which contains active compounds such as resveratrol and emodin. These components are believed to exert anti-inflammatory, uric acid-lowering, and analgesic effects. The mechanism of action involves inhibition of xanthine oxidase activity to reduce uric acid production, promotion of uric acid excretion via the kidneys, and suppression of inflammatory mediators associated with acute gout attacks. HZKL is typically prescribed in China as an oral granule preparation for patients with acute or chronic gouty arthritis or elevated serum uric acid levels.
- Brand names
- 虎杖痛风颗粒
- Other names
- HZKLPolygonum cuspidatum granules for goutHu Zhang Tong Feng Ke Li
02
Targets
XO (Xanthine Oxidoreductase)
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