Drug intelligence / Profile preview

세클원서방정375mg

Development stage
Unknown
Lead developer
Withus Pharmaceutical
Modality
Small Molecules
Administration
Oral
01

Overview

세클원서방정375mg (Cecl-One MR) is a sustained-release oral formulation of cefaclor (375 mg), a second-generation cephalosporin antibiotic developed and marketed by Withus Pharmaceutical in South Korea. It is indicated for the treatment of various bacterial infections, including acute and chronic bronchitis, pharyngitis, tonsillitis, lower urinary tract infections, and skin and soft tissue infections caused by susceptible strains of pathogens such as *Streptococcus pneumoniae*, *Haemophilus influenzae*, and *Staphylococcus aureus*. As a β-lactam antibiotic, cefaclor exerts its bactericidal activity by binding to and inhibiting penicillin-binding proteins (PBPs), which are essential enzymes involved in bacterial cell wall synthesis. This inhibition leads to cell wall weakening and subsequent bacterial lysis.

Brand names
Cecl-One MR세클원서방정375mg
Other names
cefaclor 375mg sustained-releasecefaclor375mg sustained-releasecefaclor-375mg sustained-releasecefaclor sustained-release 375mg세파클러 수화물 375mg
02

Targets

PBP (Penicillin-binding protein family)

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