Drug intelligence / Profile preview

(+)-epicatechin

Development stage
Phase 2
Modality
Small Molecules
Administration
Oral
01

Overview

(+)-epicatechin is a catechin that is flavan carrying five hydroxy substituents at positions 3, 3', 4', 5 and 7 (the 2S,3S-stereoisomer). It has a role as a cyclooxygenase 1 inhibitor and a plant metabolite. It is a catechin and a polyphenol. It is an enantiomer of (-)-epicatechin. (+)-Epicatechin has been reported in Rosa laevigata, Pavetta owariensis, and other organisms.

Other names
(+)-Epicatechind-Epicatechin(2S,3S)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triolCatechin CDexepicatechin(2S-cis)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-1-Benzopyran-3,5,7-triolent-Epicatechin(+)-epicatechol(2S,3S)-2-(3,4-dihydroxyphenyl)chroman-3,5,7-triolEpicatechin, (+)-cis-2-(3,4-Dihydroxyphenyl)chroman-3,5,7-triol
02

Targets

PGHS-1 (Prostaglandin G/H Synthase 1)

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