Drug intelligence / Profile preview

(3E)-4-(1-methyl-1H-indol-3-yl)but-3-en-2-one

Development stage
Unknown
Modality
Small Molecules
01

Overview

(3E)-4-(1-methyl–1H-indol–3–yl)but–3–en–2–one is a synthetic small molecule belonging to the n‑alkylindoles class, characterized by an indole moiety with a methyl group at the nitrogen and a butenone side chain. It has been identified as an experimental compound with potential biological activities, including anticancer and anti-inflammatory effects. Its primary known molecular target is histone acetyltransferase KAT2B, suggesting it may act as an epigenetic modulator by influencing histone acetylation and gene expression[1][4]. There are no approved therapeutic indications or marketed products containing this compound.

Other names
4-(1-methylindol-3yl)butenone(E)-4-(1-methylindole 3 yl)-3-buten 2 one1-Methyl 3-(3 oxobut 1 en 1 yl) indole(E)-4-(1-Méthyl‑1H‑indol‑3‑yl)‑3-butén‑2-one
02

Targets

KAT2B

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