(6E,11E)-heptadeca-6,11-diene-9,9-diylbis(phosphonic acid)

(6E,11E)-heptadeca-6,11-diene-9,9-diylbis(phosphonic acid) is a synthetic small molecule belonging to the bisphosphonate class. It is structurally characterized by a 17-carbon chain with two phosphonic acid groups at the 9-position and conjugated double bonds at positions 6 and 11. The compound has been studied as an experimental agent and is not approved for clinical use. Its mechanism of action involves inhibition of geranylgeranyl pyrophosphate synthase (GGPS1), an enzyme critical in the biosynthesis of geranylgeranyl pyrophosphate—a key intermediate in protein prenylation pathways. This mechanism suggests potential utility in modulating processes dependent on protein prenylation such as cell signaling or viral replication[3][5][10]. There are no known approved indications or ongoing clinical trials for this compound.

Other names

(6e,11e)-heptadeca-6,11-diene-9,9-diylbis(phosphonic acid)(6E,11E)-6,11-heptadecadiene-9,9-diylbis(phosphonic acid)[(6E,11E)-9-phosphonoheptadeca-6,11-dien-9-yl]phosphonic acid