(R)-Bicalutamide

(R)-Bicalutamide is the active enantiomer of the non-steroidal anti-androgen drug bicalutamide, which is marketed under the brand name Casodex. It is primarily used in the treatment of prostate cancer, including castration-resistant forms. This small molecule functions by antagonizing the androgen receptor, thereby inhibiting androgen-mediated signaling pathways crucial for prostate cancer cell growth. It is administered orally, slowly absorbed, and has a long plasma elimination half-life of approximately one week, with its metabolism largely mediated by cytochrome P450 enzymes.

Brand names

Casodex

Other names

r-bicalutamideR-enantiomer of bicalutamideR-isomer of bicalutamide