Drug intelligence / Profile preview

(S)-2-(phosphonoxy)caproyl-L-leucyl-p-nitroanilide

Development stage
Unknown
Modality
Peptides, Small Molecules
01

Overview

(S)-2-(Phosphonoxy)caproyl-L-leucyl-p-nitroanilide is a synthetic small molecule and peptide derivative, structurally related to leucine. It is primarily used as an experimental inhibitor of peptide deformylase, an enzyme involved in the removal of the formyl group from the N-terminal methionine of newly synthesized proteins in bacteria. This compound has been studied for its ability to bind and inhibit bacterial peptide deformylase, making it a tool compound for structural biology and enzymology research rather than a therapeutic drug candidate[2][5][8].

Other names
(S)-2-(phosphonoxy)caproyl-L-leucyl-p-nitroanilide(((1S)-1-(((1S)-3-methyl-1-((4-nitrophenyl)carbamoyl)butyl)carbamoyl)pentyl)oxy)phosphonic acid{[(1S)-1-{[(1S)-3-methyl-1-[(4-nitrophenyl)carbamoyl]butyl]carbamoyl}pentyl]oxy}phosphonic acidN-(4-nitrophenyl)-N~2~-[(2S)-2-(phosphonooxy)hexanoyl]-L-leucinamide
02

Targets

PDF (Peptide deformylase, mitochondrial)

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