1,1,1-trifluoro-3-acetamido-4-phenyl butan-2-one

1,1,1-Trifluoro-3-acetamido-4-phenyl butan-2-one (N-acetyl-L-phenylalanyl trifluoromethyl ketone) is a synthetic small molecule with the molecular formula C12H12F3NO2 and a molecular weight of approximately 259.22 g/mol[1][2][6]. It is structurally related to phenylalanine derivatives and contains a trifluoromethyl ketone moiety. This compound has been studied primarily as an experimental inhibitor of serine proteases such as chymotrypsin[7], where it acts by binding to the active site and inhibiting enzymatic activity. There are no approved therapeutic indications or clinical trials for this compound in humans; its use is limited to biochemical research as a tool compound for studying protease function[2][4][7].

Other names

N-acetyl-L-phenylalanyl trifluoromethyl ketoneN-[(2S)-4,4,4-trifluoro-3-oxo-1-phenylbutan-2-yl]acetamide